A world-wide plague turns every man, woman, and child into a mindless, cannibalistic zombie. Except for Luke James, who's completely immune to the plague but must stand helplessly by as civilization disappears around him.
As Luke wanders from city to city looking for survivors, we're witness to a hopeless, dead world. When he discovers a maximum security prison populated by the mankind's last survivors, he believes he has found an oasis. But this is no sanctuary -the prison's occupants are dominated by a power-crazy warden and his band of fanatical guards who will stop at nothing to get what they want.